Experimental Human Leprosy in the Footpad of Mice

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چکیده

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Experimental human leprosy in the footpad of mice.

Multiplication of Mycobacteria leprae in the foot­ pads of mice has been reported by Shepard . 1 o The increase has been up to 1 ,000 fold. Other workers like Chatterji4 and BergeP have also reported successful transmission of M. leprae in ra ts and mice by using differen t s trains of animals and different food and technique. Mukherj i 6, 7 has not been able to confirm their works . This work ...

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Experimental murine leprosy: growth of Mycobacterium lepraemurium in C3H and C57/BL mice after footpad inoculation.

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Experimental leprosy with nude mice.

In 1960, Shepard10) reported a model of experimental leprosy of mouse by means of footpad inoculation technic. This experimental leprosy has been widely utilized in the field of leprosy research, but grwoth of Mycobacterium leprae in normal mouse foot-pad is limited and maximum harvest of M. leprae from infected normal mouse foot-pad is about 106. Several studies were reported concerning immuno...

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ژورنال

عنوان ژورنال: Leprosy Review

سال: 1966

ISSN: 0305-7518

DOI: 10.5935/0305-7518.19660008